Venenatis
Venenatis can attack with all three forms of combat. While she will only use one combat style at a time, players in melee distance will instead only be attacked by melee. Like Vet'ion, she is weakest to crush.
She will begin the fight using 8 range attacks, followed by 8 magic attacks, all while moving position every 4 attacks. She will spawn spiderlings on the 1st range attack in cycle, and deploy her web attack on the 3rd mage attack in the cycle. This pattern will repeat until Venenatis is defeated.
All players who enter the arena will appear to the north, so it is recommended to hang south as much as possible to escape player killers, as she is no longer under level 30 Wilderness following the Wilderness boss rework. This does not apply to the weaker variant of the boss, Spindel, as her lair is still below level 30 Wilderness and can be teleported out of directly.
Guide, gear, inventory, locations, pictures and money making rates from the OSRS Wiki (CC BY-NC-SA 3.0).