Callisto
Callisto will spawn to the south of the den, right in front of the exit leading into the Escape Caves. If you wish to avoid player killers, it is recommended to place a secondary account waiting outside the entrance to scout potential threats. All players who enter the den will spawn to the north, similar to Venenatis' lair.
Callisto uses highly damaging melee attacks and is weakest to ranged attacks. Due to hitting much harder, players are recommended to range him. The first immobilizing spell (such as ice barrage) will always land if he is not already frozen, and the attacking player has equipment with a total Magic accuracy greater than or equal to 0. Binds past the first are not guaranteed to hit.
If he cannot attack with melee, he will begin using a much weaker ranged attack until he can reach his target.
Guide, gear, inventory, locations, pictures and money making rates from the OSRS Wiki (CC BY-NC-SA 3.0).